71368-80-4
- Product Name：Bromazolam
- Molecular Formula：C17H13BrN4
- Purity：99%
- Molecular Weight：353.221
Product Details
pd_meltingpoint:272.0-275℃
Bromazolam 71368-80-4 For Sale Factory Sells Reliable Quality
- Molecular Formula:C17H13BrN4
- Molecular Weight:353.221
- Melting Point:272.0-275℃
- Boiling Point:519.8±60.0 °C(Predicted)
- PKA:2.37±0.40(Predicted)
- PSA：43.07000
- Density:1.54±0.1 g/cm3 (20 oC 760 Torr)
- LogP:3.12480
71368-80-4 Relevant articles
Stereospecific anxiolytic and anticonvulsant agents with reduced muscle-relaxant, sedative-hypnotic and ataxic effects
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Page/Page column 29-30, (2008/06/13)
The present invention provides compositi...
ANXIOLYTIC AGENTS WITH REDUCED SEDATIVE AND ATAXIC EFFECTS
-
Page/Page column 38-39, (2010/02/07)
Orally active benzodiazepine derivatives...
71368-80-4 Process route
-
-
1068-57-1
acetic acid hydrazide
-
-
71368-80-4
8-bromo-1-methyl-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine
| Conditions | Yield |
|---|---|
|
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one;
With
sodium hydride;
In
tetrahydrofuran;
at 0 ℃;
for 0.333333h;
With
di-morpholin-4-yl-phosphinic acid chloride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 2h;
acetic acid hydrazide;
In
tetrahydrofuran; butan-1-ol;
at 20 ℃;
for 0.166667h;
|
40% |
-
-
1068-57-1
acetic acid hydrazide
-
![7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one](/upload/2023/8\7df4c273-daa3-4c47-be88-3fa34fd8003e.png)
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2894-61-3
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
-
-
71368-80-4
8-bromo-1-methyl-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine
| Conditions | Yield |
|---|---|
|
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one;
With
sodium hydride;
In
tetrahydrofuran;
at 0 ℃;
for 0.333333h;
With
di-morpholin-4-yl-phosphinic acid chloride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 2h;
acetic acid hydrazide;
In
tetrahydrofuran; butan-1-ol;
at 20 ℃;
for 5.16667h;
Heating / reflux;
|
40% |
71368-80-4 Upstream products
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1068-57-1
acetic acid hydrazide
-
2894-61-3
7-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
71368-80-4 Downstream products
-
612526-18-8
8-trimethylsilylacetylenyl-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]-benzodiazepine
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